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Introduction to the Book / Alexander Schuhmacher, Oliver Gassmann, Markus Hinder -- Global Epidemiological Developments / Stephan Luther, Peter Schmitz -- The Value of Pharmaceutical Innovation: Concepts and Assessment / Sam Salek, Paul Kamudoni -- A Review of the Pharmaceutical R&D Efficiency: Costs, Timelines, and Probabilities / Alexander Schuhmacher, Oliver Gassmann, Markus Hinder -- Financing Pharmaceutical Innovation / Sviataslau Sivagrakau -- Challenges and Options for Drug Discovery / Werner Kramer -- Translational Medicine: Enabling the Proof of Concepts / Gezim Lahu, John Darbyshire -- Preclinical Safety and Risk Assessment / Paul Germann, Rob Caldwell -- Developing Commercial Solutions for Therapeutic Proteins / Galina Hesse -- The Evolution of Clinical Development: From Technical Success to Clinical Value Creation / Markus Hinder, Alexander Schuhmacher -- Translational Development / Nigel McCracken -- Forty Years of Innovation in Biopharmaceuticals : Will the Next 40 Years Be as Revolutionary? / Mathias Schmidt, Sanjay Patel, Petter Veiby, Qiang Liu, Michael Buckley -- Vaccines: Where Inertia, Innovation, and Revolution Create Value, Simultaneously and Quietly / Pierre A Morgon, Hannah Nawi -- The Patient-Centric Pharma Company: Evolution, Reboot, or Revolution? / Pierre A Morgon -- The Pharmaceutical Industry is Opening Its R&D Boundaries / Alexander Schuhmacher, Ulrich A K Betz -- Out-Licensing in Pharmaceutical Research and Development / Oliver Gassmann, Carol A Krech, Martin A Bader, Gerrit Reepmeyer -- Trends and Innovations in Pharmaceutical R&D Outsourcing / Antal K Hajos -- New Innovation Models in Pharmaceutical R&D / Alexander Schuhmacher, Oliver Gassmann, Markus Hinder -- The Influence of Leadership Paradigms and Styles on Pharmaceutical Innovation / Aubyn Howard -- The Role of Modern Portfolio Management in Pharma Innovation / Joachim M Greuel, Axel Wiest -- Patent Management Throughout the Innovation Life Cycle / Martin A Bader, Oliver Gassmann.
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