서지주요정보
비이온 계면활성제가 리포솜의 안정도에 미치는 영향 = The effects of nonionic surfactants on the stability of liposomes
서명 / 저자 비이온 계면활성제가 리포솜의 안정도에 미치는 영향 = The effects of nonionic surfactants on the stability of liposomes / 강학희.
저자명 강학희 ; Kang, Hak-Hee
발행사항 [서울 : 한국과학기술원, 1988].
Online Access 원문보기 원문인쇄

소장정보

등록번호

4105381

소장위치/청구기호

학술문화관(문화관) 보존서고

MCE 8833

SMS전송

도서상태

이용가능

대출가능

반납예정일

초록정보

The effects of polyoxyethylene cetyl ethers, cholesterol, fatty alcohol on the stability of egg lecithin liposomes were investigated, observing the droplet size, light absorbance of vacant liposomes and carboxyfluorescein release from entrapped liposomes. The particle size and absorbance of liposome alone increased along the time duration, indicating that droplets unstable in nature coalesced to decrease Gibbs free energy. In surfactant systems, the size and absorbance of liposomes decreased depending on the lecithin surfactant ratio because of the formation of mixed layer or the solubilization of lecithin molecule in bilayer. Carboxyfluorescein encapsuled in pure liposome was released more rapidly by surfactants, but the release of carboxyfluorscein entrapped by liposomes with cholesterol or fatty alcohol were significantly delayed. Especially liposomes incorporated with mixture of cholesterol and cetyl alcohol slowly released the entrapped carboxyfluorescein through the membrane because of the density of bilayer and the flexibility of membrane modified by the constituents and their concentrations.

서지기타정보

서지기타정보
청구기호 {MCE 8833
형태사항 vii, 63 p. : 삽도 ; 26 cm
언어 한국어
일반주기 부록 수록
저자명의 영문표기 : Hak-Hee Kang
지도교수의 한글표기 : 김종득
지도교수의 영문표기 : Jong-Duk Kim
학위논문 학위논문(석사) - 한국과학기술원 : 화학공학과,
서지주기 참고문헌 : p. 55-58
주제 Liposomes.
계면 활성제. --과학기술용어시소러스
리포솜. --과학기술용어시소러스
Surface active reagents.
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