서지주요정보
超臨界 二酸化炭素를 利用한 日日草로부터 빈돌린 抽出에 관한 硏究 = Extraction of vindoline from catharanthus roseus by using supercritical carbon-dioxide
서명 / 저자 超臨界 二酸化炭素를 利用한 日日草로부터 빈돌린 抽出에 관한 硏究 = Extraction of vindoline from catharanthus roseus by using supercritical carbon-dioxide / 송규민.
저자명 송규민 ; Song, Gyu-Min
발행사항 [대전 : 한국과학기술원, 1992].
Online Access 원문보기 원문인쇄

소장정보

등록번호

8003015

소장위치/청구기호

학술문화관(문화관) 보존서고

MCE 92021

SMS전송

도서상태

이용가능

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초록정보

The extraction of vindoline from Catharanthus roseus using the supercritical carbon dioxide was performed in various temperature and pressure conditions. Since carbon dioxide is structurally stable and nontoxic, it was chosen as a supercritical solvent. The experimental apparatus consists mainly of four parts; the gas supply, the cosolvent supply, the extractor and the separator. Complex indole alkaloids were extracted from the leaves or the stems of Catharanthus roseus in the operating range 35~70℃ and 100~300bar. The leaves and the stems of Catharanthus roseus were dried for 24 hours in a oven and then ground to the powders. Both the sample powders and the beads (diameter 3mm, glass) were charged together in the extractor to increase mass transfer efficiency between solid particles and a carbon dioxide. The extracts were analyzed by HPLC and LC/MS spectroscopy and also the results were compared with the results obtained by the solvent extraction method. Additionally, the extraction using the supercritical carbon dioxide with ethanol as a cosolvent was also carried out in various temperature and pressure conditions and the contents of vindoline in the extracts were determined by HPLC. In this experiments, the flow rate of ethanol was 20.4㎕/min, about 3wt.% of flow rate of supercritical carbon dioxide. However the effect of ethanol on the yield of extracted vindoline was not significant. In summary, the technique of extraction of vindoline from Catharanthus roseus using the supercritical carbon dioxide was better selective for vindoline and simpler in process than that of solvent extraction.

서지기타정보

서지기타정보
청구기호 {MCE 92021
형태사항 ii, 100 p. : 삽도 ; 26 cm
언어 한국어
일반주기 부록 수록
저자명의 영문표기 : Gyu-Min Song
지도교수의 한글표기 : 홍원희
지도교수의 영문표기 : Won-Hi Hong
학위논문 학위논문(석사) - 한국과학기술원 : 화학공학과,
서지주기 참고문헌 : p. 78-84
주제 Extraction (Chemistry)
초임계 가스 추출. --과학기술용어시소러스
추출. --과학기술용어시소러스
Supercritical fluid extraction.
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