서지주요정보
협착부 후방의 전단응력이 낮은 혈관부위에서 백혈구의 유체운동에 대하여 = On the fluid-dynamic motion of leukocytes in the low shear stress region of a stenotic blood vessel
서명 / 저자 협착부 후방의 전단응력이 낮은 혈관부위에서 백혈구의 유체운동에 대하여 = On the fluid-dynamic motion of leukocytes in the low shear stress region of a stenotic blood vessel / 이은석.
발행사항 [대전 : 한국과학기술원, 2002].
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소장정보

등록번호

8012829

소장위치/청구기호

학술문화관(문화관) 보존서고

MAE 02012

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리뷰정보

초록정보

Motion of leukocytes in a pulsatile blood flow through a stenotic artery is numerically simulated by the Eulerian-Lagrangian approach. Blood is modeled by a dilute particle-suspending liquid, the particle phase representing the leukocytes and the liquid phase representing the blood plasma. The particle phase is approximated as monodispersed solid spheres and the liquid phase as one-phase Newtonian fluid. The pulsatile liquid flow is computed by PISO algorithm based on the FEM(Finite Element Method) which has second-order time accuracy. The particle trajectories are obtained by solving the equation of motion in which the force term consists of Stokes’ drag force acting on a sphere in a creeping flow. Particle motions are simulated by the SPT(Simultaneous Particle Tracking) method. The leukocyte number density(LND) on the endothelium of the blood vessel is regarded important in the atherogenesis. The LND has contradicting aspects depending on what leukocyte-endothelium interaction model we take, namely, depending on whether the particle adheres to or reflected from the wall upon its impact. In this thesis, both the two leukocyte-endothelium interaction models are taken into consideration. Time-dependent shear stress and leukocyte distribution in the pulsatile blood flow field are presented. The time-averaged values of wall shear stress and LND are also evaluated.

서지기타정보

서지기타정보
청구기호 {MAE 02012
형태사항 iii, 61 p. : 삽도 ; 26 cm
언어 한국어
일반주기 저자명의 영문표기 : Eun-Seok Lee
지도교수의 한글표기 : 장근식
지도교수의 영문표기 : Keun-Shik Chang
학위논문 학위논문(석사) - 한국과학기술원 : 항공우주공학전공,
서지주기 참고문헌 : p. 25-27
주제 협착부
맥동유동
백혈구
이상유동
피소 알고리즘
stenotic
leukocyte
particle
Eulerian-Lagrangian
pulsatile
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