Aircraft design requires the integration of several disciplines, including aerodynamics, structures, controls. But, in traditional design approach, these subsystems was treated individually, allowing little or no communication with the other subsystems. To achieve advances in performance, each technology, or discipline, must be more accurate in analysis and must be more highly integrated. One of the important interdisciplinary interactions in modern aircraft design is that of aerodynamics and structures. In this work, for increasing accuracy in each discipline's analysis, CFD for aerodynamic analysis and FEM for structural analysis was used and, for considering important interdisciplinary interactions, aeroelastic effect was considered. As optimization algorithm, PBIL algorithm was used for global optima and was parallelized to alleviate the computational burden. The efficiency and accuracy of the present method was assessed by range maximization of reference wing. The result shows that an optimum wing's performance is better than the reference wing.