In the present study, experiments have been performed to examine the behavior of a liquid spray injected eccentrically into a vertical cylinder. Spray (drop) flow pattern, drop size distribution and volume concentration have been investigated, and the results were compared with those of the concentric spray. In order to minimize the flow disturbance in spray patternation, a single-hole tube was used to collect the spray drops. The drop size and volume concentration were measured by using the Malvern particle sizer. A swirl (centrifugal) type nozzle was used in the experiments to form a spray. Generally, drop sizes appeared to be smaller in the closewall side (the space between the nozzle axis and the closest wall) than those in the opposite side. This may be due to the early wall collision (and breakup) of drops in the close-wall side. On the other hand, in the opposite side, the drops collide against the wall at far downstream location and the effect of the air recirculation was dominant. A number of drops were found floating around the upper corner of the far-wall side in the vertical cylinder. A significant number of the collided drops break up and bounce at the close-wall and fly to the far-wall side, while the rest ones flow down along the wall by the deposition ; thus the drop volume concentration curve shifts to the far-wall side, and more drops were detected there. Also the minimum point of the liquid (drop) mass flux distribution shifts to the far-wall side as the spray flows down.