A series of hydrophilic-hydrophobic copolymeric surfaces of 2-hydroxyethyl methacrylate and various alkylmethacrylate have been prepared by in-situ solution copolymerization using a redox radical initiator. Contact angles of various appropriate probing fluids on the polymeric surfaces were determined in air (hydrophobic environment) and under water (hydrophilic environment). From contact angle data, the dispersive interaction contribution ($\gamma_s^d$) and the polar contribution ($\gamma_s^p$) to the total surface free energy ($\gamma_s$) and interfacial energetic quantities (e.g., water-polymer, liquid-polymer interface, etc.) were estimated by surface and interface physicochemical theory using various approximated interfacial interaction terms. In particular, we investigated both the experimental and analytical methodologies of contact angle study in two approaches (i.e., computational and graphical method). In air measurement, the estimated results have some difference in magnitude but the energetic trends are similar and reasonable while under water measurement, the analyzed results are very similar and good agreements between the computational and graphical method were observed. From comparisons of surface energetic components between hydrophobic medium and hydrophilic one, it is found that surface and interface energetic components of polymeric surface as a representative low-energy surface are highly dependent on environmental fluid. Also, from the correlation between interfacial energetic results and recently proposed surface energetic criterion of biocompatibility, we find that HEMA/BMA, HEMA/HMA copolymer systems are in the region of biocompatibility.
2-Hydroxyethyl methacrylate와 alkylmethacrylates로 여러종류의 친수 - 소수성 공중합체를 합성하였다. 공기(소수성환경)와 수용액(친수성환경)상태에서 여러 probe liquids 로 고분자들의 Contact Angle 을 측정하였다. 측정 Contact Angle Data 로 부터, 근사-이론적 계면 상호작용항을 도입한 표면-계면 물리화학 이론을 이용해서, dispersive 와 polar 상호작용 에너지 성분을 각각 구했다.
Computational 과 Graphical한 두 방법을 이용해, Contact Angle Study 의 실험과 분석 방법론을 비교 연구하였는데, 큰 차이는 나타나지 않았다.
소수와 친수성 환경에서 얻은 에너지 성분의 비교에서, 고분자의 표면과 계면에너지 성분은 환경에 따라 큰 의존도를 나타냈다.
생체상용성에 대한 계면에너지 기준으로부터, HEMA/BMA 와 HEMA/HMA가 생체-상용영역에 속함을 알았다.
